Chronic Myelogenous Leukemia (CML) is caused due to the transformation of hematopoietic stem cells and the cardinal reason of abnormality of CML is (9;22)(q34;q11) translocation. This was primarily recognized as an abnormal chromosome and thereafter named as “Philadelphia Chromosome”. This translocation results in the Bcr-Abl fusion gene and activation of protein tyrosine kinase (PTK). Mainly, malignant transformation of Bcr-Abl is dependent on the protein tyrosine kinase (PTK) activity. Normally, c-Abl1 is involved in cellular processes and is rigorously controlled in order to prevent oncogenic activity but this activity of c-Abl1 protein is negatively regulated by its SH3 domain, and deletion of the SH3 domain results in transformation of Abl1 into an oncogene

Abstract: Juvenile delinquency is one of the serious social problem not only in under developed countries but it is equally serious problem in developed countries, though the living conditions welfare measures and development facilities are more. The reason of juvenile delinquency varies from place to place and culture to culture. In some nation poverty is the cause whereas in prosperous countries social factors are more prominent. Impact of mass media, access to new technology, materialistic culture, loose control of social values and deteriorating family system are some of the main reasons responsible for pulling children in anti social activities as per the Juvenile Justice Act. In India considerable numbers of children are engaged in criminal activities.

Nutritional status is one of the crucial indicator of health services and economic development of the nation. India is one of the countries where 40% children are mal nourished. There are various reasons for malnourishment. Due to poverty parents are not able to feed their children with appropriate nutrients, vitamins and minerals. To prevent malnutrition government of India has launched very prestigious programme “Integrated Child Development Scheme” with the assistance of UNICEF. Under this programme supplementary feeding programme, immunization, growth monitoring, health checkup, supplementation for the pregnant and lactating mothers, early childhood education etc, programmes are being provided.

The present article objective is to study the construction of a pedagogical approach and the curriculum for deployment of the Tiradentes Military Police College of Jacy-Parana - CTPMII, built through work of clearing the Jirau Hydroelectric Plant, will attend from the 6th year of elementary school to the 3rd year of high school. The Military Police of Rondonia State is responsible for the administration in partnership with the State Department of Education - SEDUC, Secretary of Security and Citizenship - SESDEC with support of the Executive Board of Preparatory Education and Care of the Army - DEPA, through the Military College of Brasilia - CMB.

Traditionally India is an agricultural nation and occupation of majority of its inhabitants has been agriculture and related activities. Even primary source of state's income was land revenue in pre-colonial India. During Mughal India administrative machinery of state i.e. Mansabdari system, was well synchronized and coordinated with the Jagirdari system, wherein land was distributed among the nobility in lieu of their salary for the military and administrative duties they were supposed to perform in service of the state.

Fibre reinforced composites due to their high stiffness to weight ratio and strength to weight ratio are being considered for liquid nitrogen cylinders. Tests have been shown that graphite/epoxy composites have tendency to micro crack at very low temperatures. In the case of cylinders these micro cracks can act as passages for the cryogenic liquid to penetrate which could ultimately lead to failure of the whole structure, hence it is very important to understand the fracture behavior of fibre composites at cryogenic temperatures before they are used in cryogenic storage systems.

Wrenn and Humber (1941) showed that the study habits are associated with scholastic achievement. Brown and Holtzman (1955) and Chauhan and Singh (1982) found that a positive relationship exists between study habits and academic achievement of school going children.Patel (1996) observed that the students who have good study habits did get significantly more achievement scores than those of poor study habits. Chauhan (2003) studied the academic achievement of high students in relation to their study habits and found study habits positively related to academic achievements. Raina (2008) studied the relationship between study habits, attitude and academic achievement of students of senior secondary schools. They found that study habits and attitudes scores were positively correlated with academic achievement of the students.

The Indian banking industry is measured as a flourishing and the secure in the banking world. The country's economy growth rate by over 9 percent since last several years and that has made it regarded as the next economic power in the world. The paper deals with the banking sector reforms and it has been discussed that India's banking industry is a mixture of public, private and foreign ownerships. The major dominance of commercial banks can be easily found in Indian banking, although the co-operative and regional rural banks have little business segment. Further the paper has discussed an evaluation of banking sector reforms and economic growth of the country since from the globalization and its effects on Indian economy.

North Kanara is a land of scenic beauty, located on the north western coast of Karnataka state, the coastal region known for sea, sand and sunshine. People come to see its panoramic environment from different parts of the world. The small emerald on the north western coast Karnataka with natural aesthetic beauty, abundant greenery, beautiful and attractive sandy beaches, temples, churches, colourful and lively feasts and festivals, the hospitable people with rich cultural milieu. All these have made the North Kanra, a prime tourist attraction not only among Indian states but also among the foreign tourists. Apart from its natural aestheticism, the region has wide range of physical and socio-cultural variations.

Quality education is all about systems that lead to good academic culture, excellent academic results, programme and adaptive management, clean administration, prominent profile of outgoing students and above all review and modification of inputs etc. The students, faculty, administrative staff, college management, parents of students and society synergize in the growth of an institution. In continuous quality pursuits all the stakeholders have a prominent role to play.

A Virtual Library has been defined by Gapen (1993) as, “the concept of remote access to the contents and services of libraries and other information resources, combining on on-site collection of current and heavily used materials in both print and electronic form, with on Electronic Network which provide access to, and delivery from, external World Wide library and commercial information contents makes virtual libraries as global symbol of the information access paradigm.

The world's biggest employment Guarantee programme Mahatma Gandhi National Rural Employment Guarantee Act (MGNREGA) was notified on 7th September 2005 and came into force from 2nd February 2006. It was launched by the Prime Minister Dr. Manmohan Singh in Anantapur District of Andhra Pradesh. Accordingly Government of Karnataka formulated the scheme MGNREGS and it came into force from 2nd February 2006. Karnataka implemented this programme in 3 phases. Around 83,517 Lakh households were given employment. MGNREGA is not just an employment provider, it is a programme designed to create rural infrastructure like roads connectivity, minor irrigation works, public buildings, water supply, water conservation and harvesting, drought relief, forestation etc. and to empower the women in rural areas, especially from the lower strata of the society.

Real-Time Polymerase Chain Reaction (PCR) is highly sensitive techniques enabling amplification and quantification of a specific nucleic acid sequence with detection of the PCR product in real time. Quantitative Real-Time PCR is the conversion of the fluorescent signals from each reaction into a numerical value for each sample. A relative quantification assay is used to analyze changes in gene expression in a given sample relative to another reference sample.

The polycrystalline samples of the mixed spinel series Ni Mg Cr Fe O with 0.5 0.5 x 2-x 4 x= 0.0, 0.2, 0.4, 0.6, 0.8, 1.0 have been prepared by standard ceramic technique and were studied by means of X-ray Diffraction and IR absorption spectroscopy. The X-ray analysis showed that the samples are formed in single-phase spinel structure. The lattice parameter 'a' obtained from X-ray diffraction data decreases with the increase of compositional parameter x. The infrared absorption spectra of all the samples of the -1 -1 series studied at room temperature in the range of 200cm - 1000cm showed two main bands. The force constants K and K have been obtained from the IR absorption data. 0 t The force constants have been observed to decrease with the internuclear separation for both the octahedral and tetrahedral sites.

The photosynthetic microalgae Haematococcus pluvialis Flotow is one of the best source of the carotenoid astaxanthin. Astaxanthin provides health benefits to humans and that is also used in mariculture feed to enhance tha color of salman flesh. The vegetative stage optimization is one of the difficult and most important step in astaxanthin production process. The potent strain of Haematococcus pluvialis Flotow collected from Pithoragarh district, Uttarakhand, India. Pithoragarh is located at 29.58°N 80.22°E. It has an average elevation of 1,514 metres (4,967 feet). In the present study, we optimised the effect of pH, light, NaNO , K HPO , NaHCO for enhanced the 3 2 4 3 vegetative growth of Haematococcus pluvialis. The maximum level of growth rate, chlorophyll a, chlorophyll b and carotenoid were observed in pH – 7.0, light - 12 hrs th Light : 12 hrs Dark, NaNO – 0.3 M, K HPO – 0.08M, NaHCO – 0.08 M. on 40 day of 3 2 4 3 incubation period.

E-banking is a general term for delivery of banking services and products through electronic channels, such as the telephone, the internet, the cell phone, etc Electronic banking helps to conduct traditional commerce through the new ways of transforming and processing information. Electronic banking saves individuals and business houses time and money. Electronic banking is one of the most successful online businesses. E- Banking allows customer to access their account and execute orders through a simple to use web site. On line banking puts the power of banking into the hands of the customer and allows the customers to self -service themselves with all their banking needs. The internet offers many opportunities to financial services.

Mathematics is an important subject of learning for all including children with hearing impairment in schools. The prescribed Mathematics textbooks contain several typical mathematical terms. Understanding and recalling of these terms play an integral role in learning Mathematics. The major factors influencing the recall of mathematical terms are familiarity, concreteness, imagery and signability (Lang & Pagliaro, 2007). The present study aimed to compare the abilities of students with and without hearing impairment in recalling the mathematical terms.

Open recruitment process is adapted by Public Sector Unit's (PSU) in India through a common entrance examination Graduate Aptitude Test for Engineers (GATE) which takes place for the field of engineering. It generally clashes with the final year examination of the colleges which posses' problems both for the company and the applicants. The research was carried out during the summer internship period at one of the leading oil companies in India at their corporate office. Due to lot of expenses involved by the company and genuine reasons by the candidates, it became necessary to find out a way that could reasonably solve the problem of both the parties involved.

Optimal nutrition is essential for athletes. Coaches could influence dietary habits of athletes,since they are important figures in the athlete's lives. The objectives of this study were to measure and compare sports nutritional knowledge of school and college coaches and to evaluate the dietary recommendations by these coaches to their athletes. In the present investigation a total sample of 70 coaches were taken with equal number of coaches training school and college athletes.. A 5-section questionnaire was developed to obtain data on demographic characteristics, weight management practices, dietary and fluid recommendations before, during and after training, knowledge on female athlete triad and sports nutrition.

This study analyzed the liquidity, solvency, efficiency and profitability of one company in Indian aviation industry. The company taken for analysis is Kingfisher Airlines Ltd. Z score has been applied to examine the financial viability and to know the financial strengths and weaknesses of the company. No doubt financial analysis sheds light for better understanding and evaluating the results of business operations and explaining how healthy a business is doing. The researcher used the Altman Z-score model with ratio analysis for this purpose.

Rumen fluid samples from adult Indian cattle (Bos indicus) were collected and observed to study the morphology of rumen ciliate protozoa belonging to genus Entodinium. The present paper deals with the morphology of a new species Entodinium commanum from the rumen of Indian cattle. The body measurements, frequency distribution and variations of the characters are recorded, critical comments are made on its specific identity, Entodinium commanum is characterized by having small size, elongated, triangular slightly curved ventrally and comma wedge shaped body with humpback appearance, body is pointed, posteriorly, Thin wedge shaped macronucleus placed high up near a adorsal lip.

The need for achieving food security is felt significantly in the recent years due to enormous pressure from the ever-increasing population in India. Food security in India has to be understood as a distress phenomenon, as with marginal increase in their incomes over time they are forced to cut down on their food consumption to meet other pressing demands of health and education that were not considered important in the past. High economic growth rates have failed to improve food security in India leaving the country facing a crisis in its rural economy. This paper is focused various issues and challenges in food security in India and food security bill for their implementation and also having drawbacks.

Psychological variables have a significant influence on the performance of athletes. Self-confidence is one of the vital factor responsible for success of the most of the athletes. The present investigation was aimed to explore differences among three levels of the hockey players represented intervarsity inter-collegiate and inter-school levels. 300 hockey players (100 in each group) were recruited as potential subjects to explore differences on the dimension of self-confidence. ANOVA was employed for statistical treatment to the obtained data collected on Sports Self-Confidence Inventory developed by Kaul and Mittal (2003).

Justice Party before it emerged as a political party, owes its origin to a social organisation called 'Madras United League' which was intended to for social uplift , amelioration of the disadvantaged people who suffered from oppression. With in a short period this League was called 'Dravidian Association'. The Justice party otherwise known as the 'South Indian Liberal Federation'was formed at the tail end of 1916.M.C.Rajah, R.Srinivasn, N.Sivaraj, R.Veeriyan, Alaelu Mangathayarammal and other Depressed Class leaders joined the Justice Party and most of them became the founding members of the Justice Party.

The Tamil demand for autonomy and security led to the militant response. The state starts to address this with violence and massacres killing for a start with 7000 Tamil civilians from 1983 to 1987. The Norwegians had drafted the text of the treaty. The united national front came victorious in December 2001 general elections. Since the President and the Prime Minister came from rival camps the Prime minister signed the agreement that had no constitutional authority to sign on war and peace .That authority rested with the political rival Kumaratunga.

Agriculture occupies a vital position in the state economy engaging about 55.89% of the total working force according in 2001 census. The conurbation the sector in the state domestic product (SDP) at constant and current prices is 10.20% and 29.70% respectively in 2010-11. This paper highlights production arrivals, Prices and values of paddy through APMC's in Raichur District following APMC's Raichur, Sindhanur Manvi , Lingasugur. Devodurga. The study is under taken for the period of often six years i.e. form 2006-07 to 2012-13. The objectives of the study are to analyze the present situation and prospects of marketing, the value transacted and price of paddy commodities.

Clarke (1976) examined that the General Motor Ability has been considered as one's level of ability in mid range of activities. It has been thought of as an interacted composite of such individual traits as Strength, Endurance, Power, Speed, Agility, Reaction time and Coordination. In successful motor performance these traits function in a coordinated manner and in effective sequence to achieve accurate and efficient movement whether it be a single effort a sin the golf drive or in a series of complexes and rapidly changing movement as in basketball.

The world has witnessed loudest screams from the side of religious dogmas. The loudest violence is in the form of religion. What has been addressed as a guest in this paper is the fact that centuries have passed, and we haven't taken the refuge of God yet. We haven't taken the roof of God because the texts which reflects to us their intellectual dialogues concluding the way of life, is kept away from the public. Bhagavad Gita has been tagged as religious book which is to be only translated to us by pastors because of our lack of enthusiasm and indoctrinated mind. This is a smashing example of the Karl Marx theory explaining the control over proletariats through superstructure.

Psychiatric disturbances affect most people in this world. Medical care is not enough to overcome these problems. What is required is the restoration of the mental health and the overall health of the patient concerned. To this effect, however, the Western approach is found to be inadequate. Instead, the Indian psychological approach to mental health and health is said to be optimal. This paper highlights, briefly though, these issues with special focus on Ayurveda and Yoga as part and parcel of the Indian psychological approach.

The mask becomes a vigorous part of contemporary culture. Being a dramatic type, it is used to hide the identity of the person. Many dramatists use this technique in their plays. Girish Karnad employs it to project the personalities of different characters. The mask in his plays shows that how the actor adopts the role playing and disguise, the mask creats the fantasy and bizzare world in his plays.

World Wide Web has created a sea change in information transfer. Information scientists have undergone a perceptible change and have become IT centered, which is evidenced by their citing pattern. This article examines the nature and pattern of citations of Information Scientists in state level seminar proceeding and one volume of an international journal in the field of the Library & Information Science. The study reveals that the trend of citations has changed over time and web citations would replace other citations in future.

First generation immigrants carry the baggage of customs and traditions along with them in the host country which often become hindrance in their integration in the new surroundings. Whereas the second generation immigrants consider the new land their own and find little or no difficulty in assimilation and acculturation. The second generation immigrants try to assimilate into the host culture.